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DeCS
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Descritor Inglês:
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Neural Cell Adhesion Molecule L1
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Descritor Espanhol:
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molécula L1 de adhesión de células nerviosas
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Descritor Português:
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Molécula L1 de Adesão de Célula Nervosa
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Sinônimos Inglês:
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CALL Protein
CamL1 Gene Product
Cell Adhesion Molecule L1
Cell Surface Glycoprotein L1
F11 Glycoprotein
Glycoprotein, NGF-Inducible
Glycoprotein, NILE
L1 Cell Adhesion Molecule
L1CAM
NGF Inducible Glycoprotein
NGF-Inducible Glycoprotein
NILE Glycoprotein
NILE Protein
Nerve Growth Factor Inducible Large External Glycoprotein
Nerve Growth Factor-Inducible Large External Glycoprotein
Neural Adhesion Molecule L1
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Categoria:
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D12.776.395.550.200.250.520.578
D12.776.543.550.200.250.520.578
D23.050.301.350.250.520.578
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Definição Inglês:
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A member of the immunoglobulin superfamily of neuronal cell adhesion molecules that is required for proper nervous system development. Neural cell adhesion molecule L1 consists of six Ig domains, five fibronectin domains, a transmembrane region and an intracellular domain. Two splicing variants are known: a neuronal form that contains a four-amino acid RSLE sequence in the cytoplasmic domain, and a non-neuronal form that lacks the RSLE sequence. Mutations in the L1 gene result in L1 disease. Neural cell adhesion molecule L1 is predominantly expressed during development in neurons and Schwann cells; involved in cell adhesion, neuronal migration, axonal growth and pathfinding, and myelination. |
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Nota Histórica Inglês:
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2003; use NEURAL CELL ADHESION MOLECULE L1 (NM) 1983-2002; for NEURAL CELL ADHESION MOLECULE L1; F11 GLYCOPROTEIN; CELL ADHESION MOLECULE L1; CAML1 GENE PRODUCT; CELL SURFACE GLYCOPROTEIN L1; L1 CELL ADHESION MOLECULE; L1 CAM & NEURAL ADHESION MOLECULE L1 use LEUKOCYTE L1 ANTIGEN COMPLEX (NM) 1992-2002; for CALL PROTEIN use LEUKOCYTE L1 ANTIGEN COMPLEX (NM) 1999-2002; for NILE PROTEIN use LEUCKCYTE L1 ANTIGEN COMPLEX (NM) 1996-2002
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Qualificadores Permitidos Inglês:
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Número do Registro:
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37447
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Identificador Único:
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D039842
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Ocorrência na BVS:
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Similar:
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DeCS
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